Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation

BACKGROUND: Synucleinopathies of the aging population are an heterogeneous group of neurological disorders that includes Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) and are characterized by the progressive accumulation of α-synuclein in neuronal and glial cells. Toll-like receptor 2...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Mol Neurodegener
Hauptverfasser: Kim, Changyoun, Spencer, Brian, Rockenstein, Edward, Yamakado, Hodaka, Mante, Michael, Adame, Anthony, Fields, Jerel Adam, Masliah, Deborah, Iba, Michiyo, Lee, He-Jin, Rissman, Robert A., Lee, Seung-Jae, Masliah, Eliezer
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085656/
https://ncbi.nlm.nih.gov/pubmed/30092810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0276-2
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge