Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms

Histiocytic neoplasms are clonal, hematopoietic disorders characterized by an accumulation of abnormal, monocyte-derived dendritic cells or macrophages in Langerhans Cell (LCH) and non-Langerhans (non-LCH) histiocytoses, respectively. The discovery of BRAFV600E mutations in ~50% of these patients pr...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Discov
Auteurs principaux: Diamond, Eli L., Durham, Benjamin H., Haroche, Julien, Yao, Zhan, Ma, Jing, Parikh, Sameer A., Wang, Zhaoming, Choi, John, Kim, Eunhee, Cohen-Aubart, Fleur, Lee, Stanley Chun-Wei, Gao, Yijun, Micol, Jean-Baptiste, Campbell, Patrick, Walsh, Michael P., Sylvester, Brooke, Dolgalev, Igor, Aminova, Olga, Heguy, Adriana, Zappile, Paul, Nakitandwe, Joy, Ganzel, Chezi, Dalton, James D., Ellison, David W., Estrada-Veras, Juvianee, Lacouture, Mario, Gahl, William A., Stephens, Philip J., Miller, Vincent A., Ross, Jeffrey S., Ali, Siraj M., Briggs, Samuel R., Fasan, Omotayo, Block, Jared, Héritier, Sebastien, Donadieu, Jean, Solit, David B., Hyman, David M., Baselga, Jose, Janku, Filip, Taylor, Barry S., Park, Christopher Y., Amoura, Zahir, Dogan, Ahmet, Emile, Jean-Francois, Rosen, Neal, Gruber, Tanja A., Abdel-Wahab, Omar
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744547/
https://ncbi.nlm.nih.gov/pubmed/26566875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-15-0913
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires