Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms

Histiocytic neoplasms are clonal, hematopoietic disorders characterized by an accumulation of abnormal, monocyte-derived dendritic cells or macrophages in Langerhans Cell (LCH) and non-Langerhans (non-LCH) histiocytoses, respectively. The discovery of BRAFV600E mutations in ~50% of these patients pr...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Diamond, Eli L., Durham, Benjamin H., Haroche, Julien, Yao, Zhan, Ma, Jing, Parikh, Sameer A., Wang, Zhaoming, Choi, John, Kim, Eunhee, Cohen-Aubart, Fleur, Lee, Stanley Chun-Wei, Gao, Yijun, Micol, Jean-Baptiste, Campbell, Patrick, Walsh, Michael P., Sylvester, Brooke, Dolgalev, Igor, Aminova, Olga, Heguy, Adriana, Zappile, Paul, Nakitandwe, Joy, Ganzel, Chezi, Dalton, James D., Ellison, David W., Estrada-Veras, Juvianee, Lacouture, Mario, Gahl, William A., Stephens, Philip J., Miller, Vincent A., Ross, Jeffrey S., Ali, Siraj M., Briggs, Samuel R., Fasan, Omotayo, Block, Jared, Héritier, Sebastien, Donadieu, Jean, Solit, David B., Hyman, David M., Baselga, Jose, Janku, Filip, Taylor, Barry S., Park, Christopher Y., Amoura, Zahir, Dogan, Ahmet, Emile, Jean-Francois, Rosen, Neal, Gruber, Tanja A., Abdel-Wahab, Omar
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744547/
https://ncbi.nlm.nih.gov/pubmed/26566875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-15-0913
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