Histone H3K36I mutation in a metastatic histiocytic tumor of the skull and response to sarcoma chemotherapy

Recurrent somatic missense mutations in histone H3 genes have been identified in subsets of pediatric cancers. H3K36 histone mutations have recently been recognized as oncogenic drivers in rare subsets of malignant soft tissue sarcomas but have not been reported in histiocytic neoplasms. Currently,...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Mol Case Stud
Main Authors: Snuderl, Matija, Dolgalev, Igor, Heguy, Adriana, Walsh, Michael F., Benayed, Ryma, Jungbluth, Achim A., Ladanyi, Marc, Karajannis, Matthias A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2019
Assuntos:
Research Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824254/
https://ncbi.nlm.nih.gov/pubmed/31645348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a004606
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