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Transcriptomic Determinants of Scrapie Prion Propagation in Cultured Ovine Microglia

Susceptibility to infection by prions is highly dependent on the amino acid sequence and host expression of the cellular prion protein (PrP(C)); however, cellular expression of a genetically susceptible PrP(C) is insufficient. As an example, it has been shown in cultured cells that permissive and re...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Muñoz-Gutiérrez, Juan F., Aguilar Pierlé, Sebastián, Schneider, David A., Baszler, Timothy V., Stanton, James B.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726464/
https://ncbi.nlm.nih.gov/pubmed/26807844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147727
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