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Transcriptomic Determinants of Scrapie Prion Propagation in Cultured Ovine Microglia

Susceptibility to infection by prions is highly dependent on the amino acid sequence and host expression of the cellular prion protein (PrP(C)); however, cellular expression of a genetically susceptible PrP(C) is insufficient. As an example, it has been shown in cultured cells that permissive and re...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Muñoz-Gutiérrez, Juan F., Aguilar Pierlé, Sebastián, Schneider, David A., Baszler, Timothy V., Stanton, James B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726464/
https://ncbi.nlm.nih.gov/pubmed/26807844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147727
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