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Limited transcriptional response of ovine microglia to prion accumulation
The conversion of normal cellular prion protein to disease-associated prion protein (PrP(Sc)) is a fundamental component of prion disease pathogenesis. The molecular mechanisms contributing to prion conversion and the impact of PrP(Sc) accumulation on cellular biology are not fully understood. To fu...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2746661/ https://ncbi.nlm.nih.gov/pubmed/19523453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.06.030 |
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