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Transcriptomic Determinants of Scrapie Prion Propagation in Cultured Ovine Microglia

Susceptibility to infection by prions is highly dependent on the amino acid sequence and host expression of the cellular prion protein (PrP(C)); however, cellular expression of a genetically susceptible PrP(C) is insufficient. As an example, it has been shown in cultured cells that permissive and re...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Muñoz-Gutiérrez, Juan F., Aguilar Pierlé, Sebastián, Schneider, David A., Baszler, Timothy V., Stanton, James B.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726464/
https://ncbi.nlm.nih.gov/pubmed/26807844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147727
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