Ex vivo propagation of infectious sheep scrapie agent in heterologous epithelial cells expressing ovine prion protein
Transmissible spongiform encephalopathies, or prion diseases, are fatal degenerative disorders of the central nervous system that affect humans and animals. Prions are nonconventional infectious agents whose replication depends on the host prion protein (PrP). Transmission of prions to cultured cell...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2001
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31178/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11259656/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.061337998 |
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