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Ex vivo propagation of infectious sheep scrapie agent in heterologous epithelial cells expressing ovine prion protein

Transmissible spongiform encephalopathies, or prion diseases, are fatal degenerative disorders of the central nervous system that affect humans and animals. Prions are nonconventional infectious agents whose replication depends on the host prion protein (PrP). Transmission of prions to cultured cell...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphov: Vilette, D., Andreoletti, O., Archer, F., Madelaine, M. F., Vilotte, J. L., Lehmann, S., Laude, H.
Materialtyp: Artigo
Språk:Inglês
Utgiven: National Academy of Sciences 2001
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31178/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11259656/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.061337998
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