Cargando...
Entrapment of a Histone Tail by a DNA Lesion in a Nucleosome Suggests the Lesion Impacts Epigenetic Marking: A Molecular Dynamics Study
[Image: see text] Errors in epigenetic markings are associated with human diseases, including cancer. We have used molecular dynamics simulations of a nucleosome containing the 10S (+)-trans-anti-B[a]P-N(2)-dG lesion, derived from the environmental pro-carcinogen benzo[a]pyrene, to elucidate the imp...
Guardado en:
| Publicado en: | Biochemistry |
|---|---|
| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American
Chemical Society
2015
|
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4721520/ https://ncbi.nlm.nih.gov/pubmed/26709619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01166 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|