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Nucleosome histone tail conformation and dynamics: impacts of lysine acetylation and a nearby minor groove benzo[a]pyrene-derived lesion

Histone tails in nucleosomes play critical roles in regulation of many biological processes including chromatin compaction, transcription and DNA repair. Moreover, post-translational modifications, notably lysine acetylation, are crucial to these functions. While the tails have been intensively stud...

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Foilsithe in:Biochemistry
Main Authors: Fu, Iwen, Cai, Yuqin, Geacintov, Nicholas E., Zhang, Yingkai, Broyde, Suse
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461660/
https://ncbi.nlm.nih.gov/pubmed/28304160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01208
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