A simple nonradioactive method for the determination of the binding affinities of antibodies induced by hapten bioconjugates for drugs of abuse

The accurate analytical measurement of binding affinities of polyclonal antibody in sera to heroin, 6-acetylmorphine (6-AM), and morphine has been a challenging task. A simple nonradioactive method that uses deuterium-labeled drug tracers and equilibrium dialysis (ED) combined with ultra performance...

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Bibliografski detalji
Izdano u:Anal Bioanal Chem
Glavni autori: Torres, Oscar B., Antoline, Joshua F. G., Li, Fuying, Jalah, Rashmi, Jacobson, Arthur E., Rice, Kenner C., Alving, Carl R., Matyas, Gary R.
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2015
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718952/
https://ncbi.nlm.nih.gov/pubmed/26677020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-015-9223-z
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