A simple nonradioactive method for the determination of the binding affinities of antibodies induced by hapten bioconjugates for drugs of abuse

The accurate analytical measurement of binding affinities of polyclonal antibody in sera to heroin, 6-acetylmorphine (6-AM), and morphine has been a challenging task. A simple nonradioactive method that uses deuterium-labeled drug tracers and equilibrium dialysis (ED) combined with ultra performance...

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Bibliografiset tiedot
Julkaisussa:Anal Bioanal Chem
Päätekijät: Torres, Oscar B., Antoline, Joshua F. G., Li, Fuying, Jalah, Rashmi, Jacobson, Arthur E., Rice, Kenner C., Alving, Carl R., Matyas, Gary R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer Berlin Heidelberg 2015
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718952/
https://ncbi.nlm.nih.gov/pubmed/26677020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-015-9223-z
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