Ligand-Based Discovery of a New Scaffold for Allosteric Modulation of the μ-Opioid Receptor

With the hope of discovering effective analgesics with fewer side effects, attention has recently shifted to allosteric modulators of the opioid receptors. In the past two years, the first chemotypes of positive or silent allosteric modulators (PAMs or SAMs, respectively) of μ- and δ-opioid receptor...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Chem Inf Model
Main Authors: Bisignano, Paola, Burford, Neil T., Shang, Yi, Marlow, Brennica, Livingston, Kathryn E., Fenton, Abigail M., Rockwell, Kristin, Budenholzer, Lauren, Traynor, John R., Gerritz, Samuel W., Alt, Andrew, Filizola, Marta
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703110/
https://ncbi.nlm.nih.gov/pubmed/26347990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.5b00388
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares