Discovery of positive allosteric modulators and silent allosteric modulators of the μ-opioid receptor

Por Burford, Neil T., Clark, Mary J., Wehrman, Tom S., Gerritz, Samuel W., Banks, Martyn, O’Connell, Jonathan, Traynor, John R., Alt, Andrew
Publicado em 2013

Ligand-Based Discovery of a New Scaffold for Allosteric Modulation of the μ-Opioid Receptor

Por Bisignano, Paola, Burford, Neil T., Shang, Yi, Marlow, Brennica, Livingston, Kathryn E., Fenton, Abigail M., Rockwell, Kristin, Budenholzer, Lauren, Traynor, John R., Gerritz, Samuel W., Alt, Andrew, Filizola, Marta
Publicado no J Chem Inf Model (2015)

Endogenous opioids regulate moment-to-moment neuronal communication and excitability

Por Winters, Bryony L., Gregoriou, Gabrielle C., Kissiwaa, Sarah A., Wells, Oliver A., Medagoda, Danashi I., Hermes, Sam M., Burford, Neil T., Alt, Andrew, Aicher, Sue A., Bagley, Elena E.
Publicado no Nat Commun (2017)

Discovery, Synthesis, and Molecular Pharmacology of Selective Positive Allosteric Modulators of the δ-Opioid Receptor

Por Burford, Neil T., Livingston, Kathryn E., Canals, Meritxell, Ryan, Molly R., Budenholzer, Lauren M. L., Han, Ying, Shang, Yi, Herbst, John J., O'Connell, Jonathan, Banks, Martyn, Zhang, Litao, Filizola, Marta, Bassoni, Daniel L., Wehrman, Tom S., Christopoulos, Arthur, Traynor, John R., Gerritz, Samuel W., Alt, Andrew
Publicado no J Med Chem (2015)