Discovery, Synthesis, and Molecular Pharmacology of Selective Positive Allosteric Modulators of the δ-Opioid Receptor

Allosteric modulators of G protein-coupled receptors (GPCRs) have a number of potential advantages compared to agonists or antagonists that bind to the orthosteric site of the receptor. These include the potential or receptor selectivity, maintenance of the temporal and spatial fidelity of signaling...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Burford, Neil T., Livingston, Kathryn E., Canals, Meritxell, Ryan, Molly R., Budenholzer, Lauren M. L., Han, Ying, Shang, Yi, Herbst, John J., O'Connell, Jonathan, Banks, Martyn, Zhang, Litao, Filizola, Marta, Bassoni, Daniel L., Wehrman, Tom S., Christopoulos, Arthur, Traynor, John R., Gerritz, Samuel W., Alt, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703104/
https://ncbi.nlm.nih.gov/pubmed/25901762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b00007
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados