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Proposed Mode of Binding and Action of Positive Allosteric Modulators at Opioid Receptors
[Image: see text] Available crystal structures of opioid receptors provide a high-resolution picture of ligand binding at the primary (“orthosteric”) site, that is, the site targeted by endogenous ligands. Recently, positive allosteric modulators of opioid receptors have also been discovered, but th...
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| Publicado no: | ACS Chem Biol |
|---|---|
| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2016
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4950826/ https://ncbi.nlm.nih.gov/pubmed/26841170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00712 |
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