Proposed Mode of Binding and Action of Positive Allosteric Modulators at Opioid Receptors

[Image: see text] Available crystal structures of opioid receptors provide a high-resolution picture of ligand binding at the primary (“orthosteric”) site, that is, the site targeted by endogenous ligands. Recently, positive allosteric modulators of opioid receptors have also been discovered, but th...

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Detaylı Bibliyografya
Yayımlandı:ACS Chem Biol
Asıl Yazarlar: Shang, Yi, Yeatman, Holly R., Provasi, Davide, Alt, Andrew, Christopoulos, Arthur, Canals, Meritxell, Filizola, Marta
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2016
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950826/
https://ncbi.nlm.nih.gov/pubmed/26841170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00712
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