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Mechanism of μ-Opioid Receptor-Magnesium Interaction and Positive Allosteric Modulation

In the era of opioid abuse epidemics, there is an increased demand for understanding how opioid receptors can be allosterically modulated to guide the development of more effective and safer opioid therapies. Among the modulators of the μ-opioid (MOP) receptor, which is the pharmacological target fo...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Hu, Xiaohu, Provasi, Davide, Ramsey, Steven, Filizola, Marta
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036724/
https://ncbi.nlm.nih.gov/pubmed/31676132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.10.007
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