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Mechanism of μ-Opioid Receptor-Magnesium Interaction and Positive Allosteric Modulation

In the era of opioid abuse epidemics, there is an increased demand for understanding how opioid receptors can be allosterically modulated to guide the development of more effective and safer opioid therapies. Among the modulators of the μ-opioid (MOP) receptor, which is the pharmacological target fo...

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Pubblicato in:Biophys J
Autori principali: Hu, Xiaohu, Provasi, Davide, Ramsey, Steven, Filizola, Marta
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036724/
https://ncbi.nlm.nih.gov/pubmed/31676132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.10.007
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