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Positive allosteric modulators of the μ-opioid receptor: a novel approach for future pain medications

Morphine and other agonists of the μ-opioid receptor are used clinically for acute and chronic pain relief and are considered to be the gold standard for pain medication. However, these opioids also have significant side effects, which are also mediated via activation of the μ-opioid receptor. Since...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Burford, N T, Traynor, J R, Alt, A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292945/
https://ncbi.nlm.nih.gov/pubmed/24460691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12599
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