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Novel GPCR paradigms at the μ-opioid receptor

Opioids, such as morphine, are the most clinically useful class of analgesic drugs for the treatment of acute and chronic pain. However, the use of opioids is greatly limited by the development of severe adverse side effects. Consequently, drug discovery efforts have been directed towards improving...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Br J Pharmacol
Hauptverfasser: Thompson, G L, Kelly, E, Christopoulos, A, Canals, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292946/
https://ncbi.nlm.nih.gov/pubmed/24460711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12600
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