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Novel GPCR paradigms at the μ-opioid receptor

Opioids, such as morphine, are the most clinically useful class of analgesic drugs for the treatment of acute and chronic pain. However, the use of opioids is greatly limited by the development of severe adverse side effects. Consequently, drug discovery efforts have been directed towards improving...

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Dettagli Bibliografici
Pubblicato in:Br J Pharmacol
Autori principali: Thompson, G L, Kelly, E, Christopoulos, A, Canals, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292946/
https://ncbi.nlm.nih.gov/pubmed/24460711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12600
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