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Heteromers of μ-δ opioid receptors: new pharmacology and novel therapeutic possibilities

Several studies suggest that heteromerization between μ (MOP) and δ (DOP) opioid receptors modulates the signalling properties of the individual receptors. For example, whereas activation of MOP receptors by an agonist induces G protein-mediated signalling, the same agonist induces β-arrestin-mediat...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Fujita, Wakako, Gomes, Ivone, Devi, Lakshmi A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292954/
https://ncbi.nlm.nih.gov/pubmed/24571499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12663
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