Activation of μ-δ opioid receptor heteromers inhibits neuropathic pain behavior in rodents

Several reports support the idea that μ- and δ-opioid receptors (ORs) may exist as heterodimers in brain regions involved in pain signaling. The unique pharmacology of these heteromers may present a novel analgesic target. However, the role of μ-δ heteromers in sensory neurons involved in pain and o...

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Veröffentlicht in:Pain
Hauptverfasser: Tiwari, Vinod, He, Shao-Qiu, Huang, Qian, Liang, Lingli, Yang, Fei, Chen, Zhiyong, Tiwari, Vineeta, Fujita, Wakako, Devi, Lakshmi A., Dong, Xinzhong, Guan, Yun, Raja, Srinivasa N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085422/
https://ncbi.nlm.nih.gov/pubmed/31815916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000001768
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