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Molecular characterization of eluxadoline as a potential ligand targeting mu-delta opioid receptor heteromers
Eluxadoline, an orally active mixed μ opioid receptor (μOR) agonist δ opioid receptor (δOR) antagonist developed for the treatment of diarrhea-predominant irritable bowel syndrome, normalizes gastrointestinal (GI) transit and defecation under conditions of novel environment stress or post-inflammato...
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| Publicado no: | Biochem Pharmacol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4769596/ https://ncbi.nlm.nih.gov/pubmed/25261794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2014.09.015 |
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