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Novel GPCR paradigms at the μ-opioid receptor

Opioids, such as morphine, are the most clinically useful class of analgesic drugs for the treatment of acute and chronic pain. However, the use of opioids is greatly limited by the development of severe adverse side effects. Consequently, drug discovery efforts have been directed towards improving...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Thompson, G L, Kelly, E, Christopoulos, A, Canals, M
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292946/
https://ncbi.nlm.nih.gov/pubmed/24460711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12600
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