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IL-2 / α-IL-2 Complex Treatment Cannot Be Substituted for the Adoptive Transfer of Regulatory T cells to Promote Bone Marrow Engraftment

Cell therapy with recipient Tregs achieves engraftment of allogeneic bone marrow (BM) without the need for cytoreductive conditioning (i.e., without irradiation or cytotoxic drugs). Thereby mixed chimerism and transplantation tolerance are established in recipients conditioned solely with costimulat...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Mahr, Benedikt, Unger, Lukas, Hock, Karin, Pilat, Nina, Baranyi, Ulrike, Schwarz, Christoph, Maschke, Svenja, Farkas, Andreas Michael, Wekerle, Thomas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701413/
https://ncbi.nlm.nih.gov/pubmed/26731275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146245
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