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Incomplete clonal deletion as prerequisite for tissue-specific minor antigen tolerization
Central clonal deletion has been considered the critical factor responsible for the robust state of tolerance achieved by chimerism-based experimental protocols, but split-tolerance models and the clinical experience are calling this assumption into question. Although clone-size reduction through de...
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| Publicado en: | JCI Insight |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5033814/ https://ncbi.nlm.nih.gov/pubmed/27699263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.85911 |
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