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Incomplete clonal deletion as prerequisite for tissue-specific minor antigen tolerization

Central clonal deletion has been considered the critical factor responsible for the robust state of tolerance achieved by chimerism-based experimental protocols, but split-tolerance models and the clinical experience are calling this assumption into question. Although clone-size reduction through de...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Pilat, Nina, Mahr, Benedikt, Unger, Lukas, Hock, Karin, Schwarz, Christoph, Farkas, Andreas M., Baranyi, Ulrike, Wrba, Fritz, Wekerle, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033814/
https://ncbi.nlm.nih.gov/pubmed/27699263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.85911
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