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IL-2 / α-IL-2 Complex Treatment Cannot Be Substituted for the Adoptive Transfer of Regulatory T cells to Promote Bone Marrow Engraftment

Cell therapy with recipient Tregs achieves engraftment of allogeneic bone marrow (BM) without the need for cytoreductive conditioning (i.e., without irradiation or cytotoxic drugs). Thereby mixed chimerism and transplantation tolerance are established in recipients conditioned solely with costimulat...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Mahr, Benedikt, Unger, Lukas, Hock, Karin, Pilat, Nina, Baranyi, Ulrike, Schwarz, Christoph, Maschke, Svenja, Farkas, Andreas Michael, Wekerle, Thomas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701413/
https://ncbi.nlm.nih.gov/pubmed/26731275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146245
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