IL-2 / α-IL-2 Complex Treatment Cannot Be Substituted for the Adoptive Transfer of Regulatory T cells to Promote Bone Marrow Engraftment

Cell therapy with recipient Tregs achieves engraftment of allogeneic bone marrow (BM) without the need for cytoreductive conditioning (i.e., without irradiation or cytotoxic drugs). Thereby mixed chimerism and transplantation tolerance are established in recipients conditioned solely with costimulat...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Mahr, Benedikt, Unger, Lukas, Hock, Karin, Pilat, Nina, Baranyi, Ulrike, Schwarz, Christoph, Maschke, Svenja, Farkas, Andreas Michael, Wekerle, Thomas
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701413/
https://ncbi.nlm.nih.gov/pubmed/26731275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146245
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