IL-2 / α-IL-2 Complex Treatment Cannot Be Substituted for the Adoptive Transfer of Regulatory T cells to Promote Bone Marrow Engraftment

Cell therapy with recipient Tregs achieves engraftment of allogeneic bone marrow (BM) without the need for cytoreductive conditioning (i.e., without irradiation or cytotoxic drugs). Thereby mixed chimerism and transplantation tolerance are established in recipients conditioned solely with costimulat...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Mahr, Benedikt, Unger, Lukas, Hock, Karin, Pilat, Nina, Baranyi, Ulrike, Schwarz, Christoph, Maschke, Svenja, Farkas, Andreas Michael, Wekerle, Thomas
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701413/
https://ncbi.nlm.nih.gov/pubmed/26731275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146245
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