Anti-Interleukin-6 Promotes Allogeneic Bone Marrow Engraftment and Prolonged Graft Survival in an Irradiation-Free Murine Transplant Model

Transfer of recipient regulatory T cells (Tregs) induces mixed chimerism and tolerance in an irradiation-free bone marrow (BM) transplantation (BMT) model involving short-course co-stimulation blockade and mTOR inhibition. Boosting endogenous Tregs pharmacologically in vivo would be an attractive al...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Granofszky, Nicolas, Farkas, Andreas M., Muckenhuber, Moritz, Mahr, Benedikt, Unger, Lukas, Maschke, Svenja, Pilat, Nina, Holly, Raimund, Wiletel, Mario, Regele, Heinz, Wekerle, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515831/
https://ncbi.nlm.nih.gov/pubmed/28769930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00821
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