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CTLA4Ig Improves Murine iTreg Induction via TGFβ and Suppressor Function In Vitro
Blockade of the CD28:CD80/86 costimulatory pathway has been shown to be potent in blocking T cell activation in vitro and in vivo. The costimulation blocker CTLA4Ig has been approved for the treatment of autoimmune diseases and transplant rejection. The therapeutic application of regulatory T cells...
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| Publicado no: | J Immunol Res |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6051081/ https://ncbi.nlm.nih.gov/pubmed/30057914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/2484825 |
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