Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage

OBJECTIVE: With no effective therapies to attenuate cartilage degeneration in osteoarthritis (OA), the result is pain and disability. Activation of hedgehog (HH) signaling causes changes related to the progression of OA, with higher levels of Gli‐mediated transcriptional activation associated with i...

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Dettagli Bibliografici
Pubblicato in:Arthritis Rheumatol
Autori principali: Ali, Shabana Amanda, Al‐Jazrawe, Mushriq, Ma, Henry, Whetstone, Heather, Poon, Raymond, Farr, Sarah, Naples, Mark, Adeli, Khosrow, Alman, Benjamin A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
Soggetti:
Osteoarthritis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690757/
https://ncbi.nlm.nih.gov/pubmed/26315393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39337
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