Targeting Stem Cell Behavior in Desmoid Tumors (Aggressive Fibromatosis) by Inhibiting Hedgehog Signaling

Desmoid tumor (also called aggressive fibromatosis) is a lesion of mesenchymal origin that can occur as a sporadic tumor or a manifestation of the preneoplastic syndrome, familial adenomatous polyposis caused by a mutation in adenomatous polyposis coli (APC). This tumor type is characterized by the...

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Autores principales: Ghanbari-Azarnier, Ronak, Sato, Shingo, Wei, Qingxia, Al-Jazrawe, Mushriq, Alman, Benjamin A
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press Inc. 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689234/
https://ncbi.nlm.nih.gov/pubmed/23814483
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