Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage

OBJECTIVE: With no effective therapies to attenuate cartilage degeneration in osteoarthritis (OA), the result is pain and disability. Activation of hedgehog (HH) signaling causes changes related to the progression of OA, with higher levels of Gli‐mediated transcriptional activation associated with i...

Full description

Saved in:
Bibliographic Details
Published in:Arthritis Rheumatol
Main Authors: Ali, Shabana Amanda, Al‐Jazrawe, Mushriq, Ma, Henry, Whetstone, Heather, Poon, Raymond, Farr, Sarah, Naples, Mark, Adeli, Khosrow, Alman, Benjamin A.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
Subjects:
Osteoarthritis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690757/
https://ncbi.nlm.nih.gov/pubmed/26315393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39337
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items