Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage

OBJECTIVE: With no effective therapies to attenuate cartilage degeneration in osteoarthritis (OA), the result is pain and disability. Activation of hedgehog (HH) signaling causes changes related to the progression of OA, with higher levels of Gli‐mediated transcriptional activation associated with i...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Ali, Shabana Amanda, Al‐Jazrawe, Mushriq, Ma, Henry, Whetstone, Heather, Poon, Raymond, Farr, Sarah, Naples, Mark, Adeli, Khosrow, Alman, Benjamin A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Osteoarthritis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690757/
https://ncbi.nlm.nih.gov/pubmed/26315393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39337
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