Intracellular cholesterol biosynthesis in enchondroma and chondrosarcoma

Enchondroma and chondrosarcoma are the most common benign and malignant cartilaginous neoplasms. Mutations in isocitrate dehydrogenase 1 and 2 (IDH1/2) are present in the majority of these tumors. We performed RNA-seq analysis on chondrocytes from Col2a1Cre;Idh1(LSL/+) animals and found that genes i...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Zhang, Hongyuan, Wei, Qingxia, Tsushima, Hidetoshi, Puviindran, Vijitha, Tang, Yuning J., Pathmanapan, Sinthu, Poon, Raymond, Ramu, Eyal, Al-Jazrawe, Mushriq, Wunder, Jay, Alman, Benjamin A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629100/
https://ncbi.nlm.nih.gov/pubmed/31039139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127232
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