Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage

OBJECTIVE: With no effective therapies to attenuate cartilage degeneration in osteoarthritis (OA), the result is pain and disability. Activation of hedgehog (HH) signaling causes changes related to the progression of OA, with higher levels of Gli‐mediated transcriptional activation associated with i...

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發表在:Arthritis Rheumatol
Main Authors: Ali, Shabana Amanda, Al‐Jazrawe, Mushriq, Ma, Henry, Whetstone, Heather, Poon, Raymond, Farr, Sarah, Naples, Mark, Adeli, Khosrow, Alman, Benjamin A.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2016
主題:
Osteoarthritis
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690757/
https://ncbi.nlm.nih.gov/pubmed/26315393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39337
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