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Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage

OBJECTIVE: With no effective therapies to attenuate cartilage degeneration in osteoarthritis (OA), the result is pain and disability. Activation of hedgehog (HH) signaling causes changes related to the progression of OA, with higher levels of Gli‐mediated transcriptional activation associated with i...

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Bibliografiske detaljer
Udgivet i:Arthritis Rheumatol
Main Authors: Ali, Shabana Amanda, Al‐Jazrawe, Mushriq, Ma, Henry, Whetstone, Heather, Poon, Raymond, Farr, Sarah, Naples, Mark, Adeli, Khosrow, Alman, Benjamin A.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690757/
https://ncbi.nlm.nih.gov/pubmed/26315393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39337
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