Evaluation of Cytarabine Against Ewing Sarcoma Xenografts by the Pediatric Preclinical Testing Program

Treatment with the nucleoside analog cytarabine has been shown to mimic changes in gene expression associated with down-regulation of the EWS-FLI1 oncogene in Ewing sarcoma cell lines, selectively inhibit their growth in vitro, and cause tumor regression in athymic nude mice. For this report cytarab...

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Detalhes bibliográficos
Publicado no:Pediatr Blood Cancer
Main Authors: Houghton, Peter J., Morton, Christopher L., Kang, Min, Reynolds, C. Patrick, Billups, Catherine A., Favours, Edward, Payne-Turner, Debbie, Tucker, Chandra, Smith, Malcolm A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675330/
https://ncbi.nlm.nih.gov/pubmed/20979180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.22355
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