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Evaluation of Cytarabine Against Ewing Sarcoma Xenografts by the Pediatric Preclinical Testing Program

Treatment with the nucleoside analog cytarabine has been shown to mimic changes in gene expression associated with down-regulation of the EWS-FLI1 oncogene in Ewing sarcoma cell lines, selectively inhibit their growth in vitro, and cause tumor regression in athymic nude mice. For this report cytarab...

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Détails bibliographiques
Publié dans:Pediatr Blood Cancer
Auteurs principaux: Houghton, Peter J., Morton, Christopher L., Kang, Min, Reynolds, C. Patrick, Billups, Catherine A., Favours, Edward, Payne-Turner, Debbie, Tucker, Chandra, Smith, Malcolm A.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675330/
https://ncbi.nlm.nih.gov/pubmed/20979180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.22355
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