Evaluation of Cytarabine Against Ewing Sarcoma Xenografts by the Pediatric Preclinical Testing Program

Treatment with the nucleoside analog cytarabine has been shown to mimic changes in gene expression associated with down-regulation of the EWS-FLI1 oncogene in Ewing sarcoma cell lines, selectively inhibit their growth in vitro, and cause tumor regression in athymic nude mice. For this report cytarab...

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Pubblicato in:Pediatr Blood Cancer
Autori principali: Houghton, Peter J., Morton, Christopher L., Kang, Min, Reynolds, C. Patrick, Billups, Catherine A., Favours, Edward, Payne-Turner, Debbie, Tucker, Chandra, Smith, Malcolm A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675330/
https://ncbi.nlm.nih.gov/pubmed/20979180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.22355
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