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Genetic Ablation of Extra Domain A of Fibronectin in Hypercholesterolemic Mice Improves Stroke Outcome by Reducing Thrombo-Inflammation

BACKGROUND: The fibronectin splicing variant containing extra domain A (Fn-EDA) is present in negligible amounts in the plasma of healthy humans, but markedly elevated in patients with comorbid conditions including diabetes and hypercholesterolemia, which are risk factors for stroke. It remains unkn...

詳細記述

保存先:
書誌詳細
出版年:Circulation
主要な著者: Dhanesha, Nirav, Ahmad, Ajmal, Prakash, Prem, Doddapattar, Prakash, Lentz, Steven R., Chauhan, Anil K.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674336/
https://ncbi.nlm.nih.gov/pubmed/26508731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.115.016540
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