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Fn- EDA in the plasma, but not endothelial cells, exacerbates stroke outcome by promoting thrombo-inflammation

BACKGROUND AND PURPOSE-: Cellular fibronectin containing extra domain A (Fn-EDA) is expressed in activated endothelial cells and elevated in circulation in patients with cardiovascular diseases. While global deficiency of Fn-EDA in mice improves stroke outcome, the specific contribution of plasma ve...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Stroke
Egile Nagusiak: Dhanesha, Nirav, Chorawala, Mehul R., Jain, Manish, Bhalla, Abhinav, Thedens, Daniel, Nayak, Manasa, Doddapattar, Prakash, Chauhan, Anil K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476677/
https://ncbi.nlm.nih.gov/pubmed/30909835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.118.023697
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