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Endothelial cell-derived von Willebrand factor, but not platelet-derived, promotes atherosclerosis in Apoe-deficient mice
OBJECTIVE: von Willebrand factor (VWF) is synthesized by endothelial cells and megakaryocytes, and is known to contribute to atherosclerosis. In vitro studies suggest that platelet-derived VWF (Plt-VWF) is biochemically and functionally different from endothelial cell-derived VWF (EC-VWF). We determ...
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| Publicat a: | Arterioscler Thromb Vasc Biol |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5823769/ https://ncbi.nlm.nih.gov/pubmed/29348121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309918 |
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