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Endothelial cell-derived VWF is the major determinant that mediates VWF-dependent acute ischemic stroke by promoting post-ischemic thrombo-inflammation
OBJECTIVE: Von Willebrand factor (VWF), which is synthesized in endothelial cells and megakaryocytes, is known to worsen stroke outcome. In vitro studies suggest that platelet-derived VWF is biochemically different from the endothelial cell-derived VWF. However, little is known about relative contri...
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| Publicado no: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5001895/ https://ncbi.nlm.nih.gov/pubmed/27444201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.307660 |
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