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ADAMTS13 retards progression of diabetic nephropathy by inhibiting intrarenal thrombosis in mice
OBJECTIVE: ADAMTS13 (A Disintegrin And Metalloprotease with Thrombospondin type I repeats-13) prevents microvascular thrombosis by cleaving prothrombogenic ultra-large von Willebrand factor (ULVWF) multimers. Clinical studies have found association between reduced ADAMTS13 specific activity, ULVWF m...
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| Publicado en: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5501287/ https://ncbi.nlm.nih.gov/pubmed/28495930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309539 |
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