ADAMTS13 retards progression of diabetic nephropathy by inhibiting intrarenal thrombosis in mice

OBJECTIVE: ADAMTS13 (A Disintegrin And Metalloprotease with Thrombospondin type I repeats-13) prevents microvascular thrombosis by cleaving prothrombogenic ultra-large von Willebrand factor (ULVWF) multimers. Clinical studies have found association between reduced ADAMTS13 specific activity, ULVWF m...

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Publicado en:Arterioscler Thromb Vasc Biol
Main Authors: Dhanesha, Nirav, Doddapattar, Prakash, Chorawala, Mehul R, Nayak, Manasa K., Kokame, Koichi, Staber, Janice M., Lentz, Steven R., Chauhan, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501287/
https://ncbi.nlm.nih.gov/pubmed/28495930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309539
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