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Targeting myeloid-cell specific integrin α9β1 inhibits arterial thrombosis in mice
Evidence suggests that neutrophils contribute to thrombosis via several mechanisms, including neutrophil extracellular traps (NETs) formation. Integrin α9β1 is highly expressed on neutrophils when compared with monocytes. It undergoes affinity upregulation on neutrophil activation, and stabilizes ad...
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| Publicado en: | Blood |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Hematology
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7068033/ https://ncbi.nlm.nih.gov/pubmed/31951649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019002846 |
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