Targeting Myeloid-Specific Integrin α9β1 Improves Short and Long-Term Stroke Outcomes in Murine Models With Preexisting Comorbidities by Limiting Thrombosis and Inflammation

RATIONALE: Currently, there is no effective intervention available that can reduce brain damage following reperfusion. Clinical studies suggest a positive correlation between the increased influx of neutrophils and severity of brain injury following reperfusion. Integrin α9β1 is highly expressed on...

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Udgivet i:Circ Res
Main Authors: Dhanesha, Nirav, Jain, Manish, Tripathi, Amit K., Doddapattar, Prakash, Chorawala, Mehul, Bathla, Girish, Nayak, Manasa K., Ghatge, Madankumar, Lentz, Steven R., Kon, Shigeyuki, Chauhan, Anil K.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7274887/
https://ncbi.nlm.nih.gov/pubmed/32195632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.120.316659
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